The US Food and Drug Administration (FDA) announced that it is recommending removing propoxyphene (Darvon, Darvocet) from the US market.
New clinical data was presented showing a risk for heart rhythm problems, with potentially serious or even fatal rhythm anomalies, resulting from using propoxyphene. This risk goes away with discontinuation of the drug - there is no apparent cumulative damage caused.
The news is significant because propoxyphene (sold as Darvon, Darvocet, and multiple generic forms of the ingredient) is a widely used opioid analgesic. An estimated 10 million patients have used this drug.
Since 2005, about 120 million prescriptions have been filled in the United States for the drugs containing propoxyphene. They have been sold since 1957 and are popular with older Americans. Their usage has waned due to newer drugs for moderate pain.
The United kingdom banned the drugs in 2005, and the European Union followed in 2009, based on evidence that propoxyphene was harmful. Why has it taken the FDA so long to take action on this dangerous drug. What else is out there that is killing people when they think its helping them.
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